Rates of fatty acid oxidations by P450 compound I are pH dependent.

ABSTRACT: The rates of oxidation of fatty acids by CYP119 compound I were dependent on the pH of the medium. The plot shows log k values for reactions of acids as a function of pH, where the slopes indicate mixed third-order and fourth-order dependence on base concentration. For palmitic acid, the rate increased 50-fold over the pH range 6.8-7.3.

SUBMITTER: Su Z 

PROVIDER: S-EPMC3477493 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature