Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance.

ABSTRACT: Easy to find: magnetic nanoparticles bearing fluorochromes (red) that intercalate with DNA (green) form microaggregates with DNA generated by the polymerase chain reaction (PCR). These aggregates can be detected at low cycle numbers by magnetic resonance (MR).

SUBMITTER: Alcantara D 

PROVIDER: S-EPMC3477829 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature