Neuroprotection for treatment of glaucoma in adults.

ABSTRACT:

Background

Glaucoma is a heterogeneous group of conditions involving progressive damage to the optic nerve, deterioration of retinal ganglion cells and ultimately visual field loss. It is a leading cause of blindness worldwide. Open angle glaucoma (OAG), the commonest form of glaucoma, is a chronic condition that may or may not present with increased intraocular pressure (IOP). Neuroprotection for glaucoma refers to any intervention intended to prevent optic nerve damage or cell death. The treatment can target extracellular factors such as reducing IOP, or cellular factors derived from the optic nerve itself such as blocking intracellular death signals.

Objectives

The objective of this review was to systematically examine the evidence regarding the effectiveness of neuroprot

SUBMITTER: Sena DF 

PROVIDER: S-EPMC3478138 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature