Iron-catalyzed alkylations of aryl sulfamates and carbamates.

ABSTRACT: The alkylation of aryl sulfamates and carbamates using iron catalysis is reported. The method constructs sp(2)-sp(3) carbon-carbon bonds and provides synthetically useful yields across a range of substrates (>35 examples). The directing group ability of sulfamates and carbamates, accompanied by their low reactivity toward conventional cross-couplings, renders these substrates useful for the synthesis of polyfunctionalized arenes.

SUBMITTER: Silberstein AL 

PROVIDER: S-EPMC3479317 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature