Apparent diffusion coefficient measurements in the differentiation between benign and malignant lesions: a systematic review.

ABSTRACT:

Objectives

To systematically review the value of apparent diffusion coefficient (ADC) measurement in the differentiation between benign and malignant lesions.

Methods

A systematic search of the Medline/Pubmed and Embase databases revealed 109 relevant studies. Quality of these articles was assessed using the Quality Assessment of the Studies of Diagnostic Accuracy Included in Systematic Reviews (QUADAS) criteria. Reported ADC values of benign and malignant lesions were compared per organ.

Results

The mean quality score of the reviewed articles was 50%. Comparison of ADC values showed marked variation among studies and between benign and malignant lesions in various organs. In several organs, such as breast, liver, and uterus, ADC values discriminated well between beni

SUBMITTER: Vermoolen MA 

PROVIDER: S-EPMC3481080 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature