Prognostic factors in canine appendicular osteosarcoma - a meta-analysis.

ABSTRACT:

Background

Appendicular osteosarcoma is the most common malignant primary canine bone tumor. When treated by amputation or tumor removal alone, median survival times (MST) do not exceed 5 months, with the majority of dogs suffering from metastatic disease. This period can be extended with adequate local intervention and adjuvant chemotherapy, which has become common practice. Several prognostic factors have been reported in many different studies, e.g. age, breed, weight, sex, neuter status, location of tumor, serum alkaline phosphatase (SALP), bone alkaline phosphatase (BALP), infection, percentage of bone length affected, histological grade or histological subtype of tumor. Most of these factors are, however, only reported as confounding factors in larger studies. Insight in trul

SUBMITTER: Boerman I 

PROVIDER: S-EPMC3482154 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature