Mutational bias and translational selection shaping the codon usage pattern of tissue-specific genes in rice.

ABSTRACT: The regulatory mechanisms of determining which genes specifically expressed in which tissues are still not fully elucidated, especially in plants. Using internal correspondence analysis, I first establish that tissue-specific genes exhibit significantly different synonymous codon usage in rice, although this effect is weak. The variability of synonymous codon usage between tissues accounts for 5.62% of the total codon usage variability, which has mainly arisen from the neutral evolutionary forces, such as GC content variation among tissues. Moreover, tissue-specific genes are under differential selective constraints, inferring that natural selection also contributes to the codon usage divergence between tissues. These findings may add further evidence in understanding the differentiation a

SUBMITTER: Liu Q 

PROVIDER: S-EPMC3483185 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature