Identification of gene expression changes associated with long-term memory of courtship rejection in Drosophila males.

ABSTRACT: Long-term memory formation in Drosophila melanogaster is an important neuronal function shaping the insect's behavioral repertoire by allowing an individual to modify behaviors on the basis of previous experiences. In conditioned courtship or courtship suppression, male flies that have been repeatedly rejected by mated females during courtship advances are less likely than naïve males to subsequently court another mated female. This long-term courtship suppression can last for several days after the initial rejection period. Although genes with known functions in many associative learning paradigms, including those that function in cyclic AMP signaling and RNA translocation, have been identified as playing critical roles in long-term conditioned courtship, it is clear that additional mecha

SUBMITTER: Winbush A 

PROVIDER: S-EPMC3484674 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature