Aetiology of community-acquired neonatal sepsis in low and middle income countries.

ABSTRACT:

Background

99% of the approximate 1 million annual neonatal deaths from life-threatening invasive bacterial infections occur in developing countries, at least 50% of which are from home births or community settings. Data concerning aetiology of sepsis in these settings are necessary to inform targeted therapy and devise management guidelines. This review describes and analyses the bacterial aetiology of community-acquired neonatal sepsis in developing countries.

Methods

A search of Medline, Embase, Global Health and Web of Knowledge, limited to post-1980, found 27 relevant studies. Data on aetiology were extracted, tabulated and analysed along with data on incidence, risk factors, case fatality rates and antimicrobial sensitivity.

Results

The most prevalent pathogens

SUBMITTER: Waters D 

PROVIDER: S-EPMC3484773 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature