Stochastic simulations of a synthetic bacteria-yeast ecosystem.

ABSTRACT:

Background

The field of synthetic biology has greatly evolved and numerous functions can now be implemented by artificially engineered cells carrying the appropriate genetic information. However, in order for the cells to robustly perform complex or multiple tasks, co-operation between them may be necessary. Therefore, various synthetic biological systems whose functionality requires cell-cell communication are being designed. These systems, microbial consortia, are composed of engineered cells and exhibit a wide range of behaviors. These include yeast cells whose growth is dependent on one another, or bacteria that kill or rescue each other, synchronize, behave as predator-prey ecosystems or invade cancer cells.

Results

In this paper, we study a synthetic ecosystem comprisi

SUBMITTER: Biliouris K 

PROVIDER: S-EPMC3485176 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature