Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos).

ABSTRACT:

Background

Radiofrequency ablation (RFA) is effective for treating Barrett's esophagus (BE) but often involves multiple endoscopy sessions over several months to achieve complete response.

Objective

Identify structural markers that correlate with treatment response by using 3-dimensional (3-D) optical coherence tomography (OCT; 3-D OCT).

Design

Cross-sectional.

Setting

Single teaching hospital.

Patients

Thirty-three patients, 32 male and 1 female, with short-segment (<3 cm) BE undergoing RFA treatment.

Intervention

Patients were treated with focal RFA, and 3-D OCT was performed at the gastroesophageal junction before and immediately after the RFA treatment. Patients were re-examined with standard endoscopy 6 to 8 weeks later and had biopsies to ru

SUBMITTER: Tsai TH 

PROVIDER: S-EPMC3485415 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature