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In vitro activities of nine antifungal drugs against 81 Phialophora and Cyphellophora isolates.


ABSTRACT: Cyphellophora guyanensis (n = 15), other Cyphellophora species (n = 11), Phialophora europaea (n = 43), and other Phialophora species (n = 12) were tested in vitro against nine antifungal drugs. The MIC(90)s across all of the strains (n = 81) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.5 μg/ml; voriconazole, 1 μg/ml; micafungin, 1 μg/ml; terbinafine, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 4 μg/ml; fluconazole, 8 μg/ml; amphotericin B, 16 μg/ml.

SUBMITTER: Feng P 

PROVIDER: S-EPMC3486609 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature