Cost-effectiveness of cervical cancer screening: cytology versus human papillomavirus DNA testing.

ABSTRACT:

Objective

To determine the most cost-effective screening programme for cervical cancer.

Design

Cost-effectiveness analysis from a societal perspective.

Setting

The Netherlands.

Population

Dutch women who have not been invited for human papillomavirus (HPV) vaccination.

Methods

We calibrated the microsimulation screening analysis (MISCAN) model to Dutch epidemiological data. We used this model to consider nine screening strategies that use: (i) cytological testing with cytology triage for borderline/mildly abnormal smears; (ii) HPV testing with cytology triage for HPV-positive smears; or (iii) cytological testing with HPV triage for borderline/mildly abnormal smears. For each strategy, we varied the number of screening rounds, the time interval, the age o

SUBMITTER: van Rosmalen J 

PROVIDER: S-EPMC3489039 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature