Population structure of Aggarwals of north India as revealed by molecular markers.
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ABSTRACT:
SUBMITTER: Gupta V
PROVIDER: S-EPMC3490109 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Publications
Population structure of Aggarwals of north India as revealed by molecular markers.
Gupta Vipin V Khadgawat Rajesh R Ng Hon Keung Tony HK Kumar Satish S Rao Vadlamudi Raghavendra VR Sachdeva Mohinder Pal MP
Genetic testing and molecular biomarkers 20101028 6
Using molecular genetic data on Aggarwals (Vaish/Vysya), an endogamous population group of north India, we provide evidence of its homogeneous unstratified population structure. We found the mean average heterozygosity value of 0.33 for 14 single nucleotide polymorphisms belonging to four genes (TCF7L2-, HHEX-, KCNJ11-, and ADIPOQ-) in the Aggarwal population (sample of 184 individuals) and tried to evaluate the genomic efficiency of endogamy in this population with the help of clan-based strati ...[more]
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