A prospective study of frailty in nephrology-referred patients with CKD.

ABSTRACT:

Background

Frailty is a construct developed to characterize a state of reduced functional capacity in older adults. However, there are limited data describing the prevalence or consequences of frailty in middle-aged patients with chronic kidney disease (CKD).

Study design

Observational study.

Setting & participants

336 non-dialysis-dependent patients with stages 1-4 CKD with estimated glomerular filtration rate (eGFR) <90 mL/min/1.73 m(2) (by the CKD-EPI [CKD Epidemiology Collaboration] serum creatinine-based equation) or evidence of microalbuminuria enrolled in the Seattle Kidney Study, a clinic-based cohort study. Findings were compared with community-dwelling older adults in the Cardiovascular Health Study.

Outcome

Prevalence and determinants of frailty in a

SUBMITTER: Roshanravan B 

PROVIDER: S-EPMC3491110 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature