Isolation and mutation trend analysis of influenza A virus subtype H9N2 in Egypt.

ABSTRACT:

Background

Avian influenza virus H9N2 is a panzootic pathogen that affects poultry causing mild to moderate respiratory distress but has been associated with high morbidity and considerable mortality. Interspecies transmission of H9N2 from avian species to mammalian hosts does occur. The virus possesses human virus-like receptor specificity and it can infect humans producing flu-like illness.

Methods

Recently, mild influenza like symptoms were detected in H5N1 vaccinated flocks. Influenza A subtype H9N2 was isolated from the infected flock. The virus evolution was investigated by sequencing the viral genes to screen the possible virus recombination. The viral amino acid sequences from the isolated H9N2 strains were compared to other related sequences from the flu data base t

SUBMITTER: Abdel-Moneim AS 

PROVIDER: S-EPMC3492205 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature