Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree.

ABSTRACT: One hundred and forty-six previously detected mutations were more precisely positioned in the human Y chromosome phylogeny by the analysis of 51 representative Y chromosome haplogroups and the use of 59 mutations from literature. Twenty-two new mutations were also described and incorporated in the revised phylogeny. This analysis made it possible to identify new haplogroups and to resolve a deep trifurcation within haplogroup B2. Our data provide a highly resolved branching in the African-specific portion of the Y tree and support the hypothesis of an origin in the north-western quadrant of the African continent for the human MSY diversity.

SUBMITTER: Scozzari R 

PROVIDER: S-EPMC3492319 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature