Sleep spindles are locally modulated by training on a brain-computer interface.
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ABSTRACT:
SUBMITTER: Johnson LA
PROVIDER: S-EPMC3494921 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
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Sleep spindles are locally modulated by training on a brain-computer interface.
Johnson Lise A LA Blakely Tim T Hermes Dora D Hakimian Shahin S Ramsey Nick F NF Ojemann Jeffrey G JG
Proceedings of the National Academy of Sciences of the United States of America 20121022 45
The learning of a motor task is known to be improved by sleep, and sleep spindles are thought to facilitate this learning by enabling synaptic plasticity. In this study subjects implanted with electrocorticography (ECoG) arrays for long-term epilepsy monitoring were trained to control a cursor on a computer screen by modulating either the high-gamma or mu/beta power at a single electrode located over the motor or premotor area. In all trained subjects, spindle density in posttraining sleep was i ...[more]
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