Identification of VanN-type vancomycin resistance in an Enterococcus faecium isolate from chicken meat in Japan.

ABSTRACT: Five VanN-type vancomycin-resistant Enterococcus faecium strains were isolated from a sample of domestic chicken meat in Japan. All isolates showed low-level resistance to vancomycin (MIC, 12 mg/liter) and had the same pulsed-field gel electrophoresis profile. The vancomycin resistance was encoded on a large plasmid (160 kbp) and was expressed constitutively. The VanN-type resistance operon was identical to the first resistance operon to be reported, with the exception of a 1-bp deletion in vanT(N) and a 1-bp substitution in vanS(N).

SUBMITTER: Nomura T 

PROVIDER: S-EPMC3497174 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature