Prevalence of and risk factors for anal human papillomavirus infection among young healthy women in Costa Rica.

ABSTRACT:

Background

Anal cancer is caused by human papillomavirus (HPV), yet little is known about anal HPV infection among healthy young women.

Methods

A total of 2017 sexually active women in the control arm of an HPV-16/18 vaccine trial had a single anal specimen collected by a clinician at the 4-year study visit. Samples were tested for HPV by SPF(10) PCR/DEIA/LiPA(25), version 1.

Results

A total of 4% of women had HPV-16, 22% had oncogenic HPV, and 31% had any HPV detected in an anal specimen. The prevalence of anal HPV was higher among women who reported anal intercourse, compared with those who did not (43.4% vs 28.4%; P< .001). Among women who reported anal intercourse, cervical HPV (adjusted odds ratio [aOR], 5.3 [95% confidence interval {CI}, 3.4-8.2]), number of sex

SUBMITTER: Castro FA 

PROVIDER: S-EPMC3499109 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature