Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging.

ABSTRACT:

Objective

Surgical treatment of focal epilepsy in patients with focal cortical dysplasia (FCD) is most successful if all epileptogenic tissue is resected. This may not be evident on structural magnetic resonance imaging (MRI), so intracranial electroencephalography (icEEG) is needed to delineate the seizure onset zone (SOZ). EEG-functional MRI (fMRI) can reveal interictal discharge (IED)-related hemodynamic changes in the irritative zone (IZ). We assessed the value of EEG-fMRI in patients with FCD-associated focal epilepsy by examining the relationship between IED-related hemodynamic changes, icEEG findings, and postoperative outcome.

Methods

Twenty-three patients with FCD-associated focal epilepsy undergoing presurgical evaluation including icEEG underwent simultaneous EEG-

SUBMITTER: Thornton R 

PROVIDER: S-EPMC3500670 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature