A versatile method for generating semiconducting polymer dot nanocomposites.

ABSTRACT: This paper describes a method, based on co-precipitation, for generating small semiconducting polymer dot (Pdot) nanocomposites, which contain either gold or iron oxide nanoparticles within the Pdot matrix. We demonstrate the utility of Pdot-Au nanoparticles (Au-NP-Pdots) in dual-modality imaging in which co-localization of fluorescence from Pdot and scattering from Au was used to identify Au-NP-Pdot probes for downstream single-particle tracking and cellular imaging. We also demonstrate the potential of employing Pdot-FeO(x) nanoparticles (FeO(x)-NP-Pdots) for both sample preparation, where cells tagged with FeO(x)-NP-Pdots were isolated using an external magnet, and cellular imaging and detection, owing to the intense fluorescence from Pdots. The method we present here should be generali

SUBMITTER: Sun W 

PROVIDER: S-EPMC3500905 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature