Creating females? Developmental effects of 17α-ethynylestradiol on the mangrove rivulus' ovotestis.

ABSTRACT: Interest in the occurrence and fate of trace organic contaminants in the aquatic environment and their potential effects on all organisms has increased over the past two decades. Researches on contaminants have included both natural and synthetic estrogenic contaminants, neuroactive pharmaceuticals, and other endocrine disrupting chemicals that are mediated by the androgen and progesterone receptors. Exposure to very low concentrations (ng/L or parts per trillion) of compounds such as 17α-ethynylestradiol (EE(2)), a synthetic estrogen, can affect gonadal development, viability and production of eggs, fertilization rate, and sexual differentiation in fishes. Researchers and aquaculturists have used exposures to relatively higher concentrations of androgens and estrogens, for example 17α-met

SUBMITTER: Farmer JL 

PROVIDER: S-EPMC3501100 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature