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Staphylococcus aureus CC398 clade associated with human-to-human transmission.

ABSTRACT: Staphylococcus aureus clonal complex 398 (CC398) isolates colonize livestock and can spread to human contacts. Genetic analysis of isolates epidemiologically associated with human-to-human, but not livestock, transmission in multiple countries and continents identified a common clade that was negative for tet(M) and positive for bacteriophage 3. Another group of human-to-human-transmitted isolates belonged to the common livestock-associated clade but had acquired a unique 7 bacteriophage.

SUBMITTER: McCarthy AJ 

PROVIDER: S-EPMC3502926 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Staphylococcus aureus CC398 clade associated with human-to-human transmission.

McCarthy Alex J AJ   van Wamel Willem W   Vandendriessche Stien S   Larsen Jesper J   Denis Olivier O   Garcia-Graells Cristina C   Uhlemann Ann-Catrin AC   Lowy Franklin D FD   Skov Robert R   Lindsay Jodi A JA  

Applied and environmental microbiology 20121005 24

Staphylococcus aureus clonal complex 398 (CC398) isolates colonize livestock and can spread to human contacts. Genetic analysis of isolates epidemiologically associated with human-to-human, but not livestock, transmission in multiple countries and continents identified a common clade that was negative for tet(M) and positive for bacteriophage 3. Another group of human-to-human-transmitted isolates belonged to the common livestock-associated clade but had acquired a unique 7 bacteriophage. ...[more]

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