Allele-specific PCR for determination of IL28B genotype.

ABSTRACT: The IL28B genotype is a critical determinant of interferon response in patients infected with hepatitis C virus genotype 1. We describe an allele-specific PCR assay for the IL28B genotype. The assay is simple and robust, uses commonly available real-time PCR instrumentation, and is well suited for clinical laboratories offering IL28B genotyping.

SUBMITTER: Cook L 

PROVIDER: S-EPMC3502971 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature