MscS-Like10 is a stretch-activated ion channel from Arabidopsis thaliana with a preference for anions.

ABSTRACT: Like many other organisms, plants are capable of sensing and responding to mechanical stimuli such as touch, osmotic pressure, and gravity. One mechanism for the perception of force is the activation of mechanosensitive (or stretch-activated) ion channels, and a number of mechanosensitive channel activities have been described in plant membranes. Based on their homology to the bacterial mechanosensitive channel MscS, the 10 MscS-Like (MSL) proteins of Arabidopsis thaliana have been hypothesized to form mechanosensitive channels in plant cell and organelle membranes. However, definitive proof that MSLs form mechanosensitive channels has been lacking. Here we used single-channel patch clamp electrophysiology to show that MSL10 is capable of providing a MS channel activity when heterologously

SUBMITTER: Maksaev G 

PROVIDER: S-EPMC3503204 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature