The value of pancreatic stone protein in predicting acute appendicitis in patients presenting at the emergency department with abdominal pain.

ABSTRACT:

Background

Pancreatic Stone Protein (PSP) is a protein naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that blood PSP levels rise in the presence of inflammation or infection. However, it is not known whether PSP is superior to other established blood tests (e.g. White Blood Count, Neutrophils or C - reactive protein) in predicting appendicitis in patients presenting with abdominal pain and a clinical suspicion of appendicitis at the emergency room.

Methods/design

The PSP Appendix Trial is a prospective, multi-center, cohort study to assess the value of PSP in the diagnostic workup of acute appendicitis. 245 patients will be prospectively recruited. Interim analysis will be performed once 123 patients are recruit

SUBMITTER: Tschuor C 

PROVIDER: S-EPMC3503734 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature