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Supramaximal elevation in B-type natriuretic peptide and its N-terminal fragment levels in anephric patients with heart failure: a case series.


ABSTRACT:

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Introduction

Little is known about the responses of natriuretic peptides to developing congestive heart failure in 'anephric' end-stage kidney disease.

Case presentation

We present three consecutive cases of surgically-induced anephric patients in a critical care environment: a 28-year-old Caucasian woman (with congestive heart failure), a 42-year-old Caucasian woman (without congestive heart failure), and a 23-year-old Caucasian woman (without congestive heart failure). Our limited study data indicate that cut-off values advocated for B-type natriuretic peptide and its N-terminal fragment to 'rule out' congestive heart failure in two of our end-stage kidney disease patients (without congestive heart failure) are largely appropriate for anephric patients.

SUBMITTER: Ting JY 

PROVIDER: S-EPMC3506524 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature