Age-related changes in aortic arch geometry: relationship with proximal aortic function and left ventricular mass and remodeling.

ABSTRACT:

Objectives

We sought to define age-related geometric changes of the aortic arch and determine their relationship to central aortic stiffness and left ventricular (LV) remodeling.

Background

The proximal aorta has been shown to thicken, enlarge in diameter, and lengthen with aging in humans. However, no systematic study has described age-related longitudinal and transversal remodeling of the aortic arch and their relationship with LV mass and remodeling.

Methods

We studied 100 subjects (55 women, 45 men, average age 46 ± 16 years) free of overt cardiovascular disease using magnetic resonance imaging to determine aortic arch geometry (length, diameters, height, width, and curvature), aortic arch function (local aortic distensibility and arch pulse wave velocity [PWV]),

SUBMITTER: Redheuil A 

PROVIDER: S-EPMC3508703 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature