Crystallization of the DdrB-DNA complex from Deinococcus radiodurans.

ABSTRACT: The remarkable ability of members of the Deinococcus family to recover from extreme DNA damage is in part owing to their robust DNA-repair mechanisms. Of particular interest is their ability to repair hundreds of double-strand DNA breakages through a rapid and efficient mechanism involving novel proteins that are uniquely found in Deinococcus spp. One such protein, DdrB, which is thought to play a role early in DSB repair, has been crystallized in complex with ssDNA and data have been collected to 2.3?Å resolution.

SUBMITTER: Sugiman-Marangos S 

PROVIDER: S-EPMC3509982 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature