Modeling dynamic introduction of Chikungunya virus in the United States.

ABSTRACT: Chikungunya is a mosquito-borne viral infection of humans that previously was confined to regions in central Africa. However, during this century, the virus has shown surprising potential for geographic expansion as it invaded other countries including more temperate regions. With no vaccine and no specific treatment, the main control strategy for Chikungunya remains preventive control of mosquito populations. In consideration for the risk of Chikungunya introduction to the US, we developed a model for disease introduction based on virus introduction by one individual. Our study combines a climate-based mosquito population dynamics stochastic model with an epidemiological model to identify temporal windows that have epidemic risk. We ran this model with temperature data from different loca

SUBMITTER: Ruiz-Moreno D 

PROVIDER: S-EPMC3510155 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature