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Arylglycine-derivative synthesis via oxidative sp(3) C-H functionalization of α-amino esters.

ABSTRACT: An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with α-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives in satisfactory yields.

SUBMITTER: Xu Z

PROVIDER: S-EPMC3510987 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Arylglycine-derivative synthesis via oxidative sp(3) C-H functionalization of α-amino esters.

Xu Zhanwei Z Yu Xiaoqiang X Feng Xiujuan X Bao Ming M

Beilstein journal of organic chemistry 20120918

An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with α-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives in satisfactory yields. ...[more]

PMID: 23209487

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