Asymmetric desymmetrization of meso-diols by C(2)-symmetric chiral 4-pyrrolidinopyridines.

ABSTRACT: In this work we developed C(2)-symmetric chiral nucleophilic catalysts which possess a pyrrolidinopyridine framework as a catalytic site. Some of these organocatalysts effectively promoted asymmetric desymmetrization of meso-diols via enantioselective acylation.

SUBMITTER: Schedel H 

PROVIDER: S-EPMC3511012 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature