Asymmetric Bronsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene.

ABSTRACT: A new chiral Brønsted acid-catalyzed aza-Diels-Alder reaction of cyclic C-acylimines with cyclopentadiene has been developed. The reaction provides optically active aza-tetracycles in good yields with high diastereo- and enantioselectivities under mild reaction conditions.

SUBMITTER: Rueping M 

PROVIDER: S-EPMC3511017 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature