Health-related quality of life in different stages of chronic kidney disease and at initiation of dialysis treatment.

ABSTRACT:

Objectives

To evaluate health-related quality of life (HRQoL) in patients in different stages of chronic kidney disease (CKD) up to initiation of dialysis treatment and to explore possible correlating and influencing factors.

Methods

Cross-sectional design with 535 patients in CKD stages 2-5 and 55 controls assessed for HRQoL through SF-36 together with biomarkers.

Results

All HRQoL dimensions deteriorated significantly with CKD stages with the lowest scores in CKD 5. The largest differences between the patient groups were seen in 'physical functioning', 'role physical', 'general health' and in physical summary scores (PCS). The smallest disparities were seen in mental health and pain. Patients in CKD stages 2-3 showed significantly decreased HRQoL compared to matched

SUBMITTER: Pagels AA 

PROVIDER: S-EPMC3511211 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature