Impact of high-risk sex and focused interventions in heterosexual HIV epidemics: a systematic review of mathematical models.

ABSTRACT:

Background

The core-group theory of sexually transmitted infections suggests that targeting prevention to high-risk groups (HRG) could be very effective. We aimed to quantify the contribution of heterosexual HRGs and the potential impact of focused interventions to HIV transmission in the wider community.

Methods

We systematically identified studies published between 1980 and 2011. Studies were included if they used dynamical models of heterosexual HIV transmission, incorporated behavioural heterogeneity in risk, and provided at least one of the following primary estimates in the wider community (a) the population attributable fraction (PAF) of HIV infections due to HRGs, or (b) the number per capita or fraction of HIV infections averted, or change in HIV prevalence/incidenc

SUBMITTER: Mishra S 

PROVIDER: S-EPMC3511305 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature