Identification and evaluation of anti hepatitis C virus phytochemicals from Eclipta alba.

ABSTRACT:

Ethnopharmacological relevance

Eclipta alba, traditionally known as bhringraj, has been used in Ayurvedic medicine for more than 1000 years in India. It is used for the treatment of infective hepatitis, liver cirrhosis, liver enlargement and other ailments of liver and gall bladder in India. The aim of this study was to evaluate anti-hepatitis C virus activity present in the Eclipta alba extract, perform bioassay based fractionation and identify anti-HCV phytochemicals from the active fractions.

Materials and methods

Identification of active compounds was performed by bio-activity guided fractionation approach. Active isolates were separated by the combination of silica gel chromatography and preparative scale reverse phase HPLC. Eclipta alba extract and its isolates were ex

SUBMITTER: Manvar D 

PROVIDER: S-EPMC3511619 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature