Mortality and causes of death in the Familial Intracranial Aneurysm study.

ABSTRACT:

Background

Higher mortality for patients with aneurysmal subarachnoid haemorrhage has been reported.

Aims

In families with intracranial aneurysms, we sought to determine whether mortality among subjects with intracranial aneurysm (affected) was higher and related to rupture, compared with unaffected family members.

Methods

Subjects enrolled in the Familial Intracranial Aneurysm protocol were contacted yearly and their status was obtained. If reported to be deceased, the cause of death was verified by available records. A Cox proportional hazards model was utilized to compare mortality rates.

Results

Of the 2794 subjects, 1073 were affected and 1721 were unaffected. There were 8525 person-years of follow-up (mean 3·05 ± 1·73 years) and 85 deaths. Age at study en

SUBMITTER: Sauerbeck L 

PROVIDER: S-EPMC3511628 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature