Corneal endothelial cell changes 5 years after laser in situ keratomileusis: femtosecond laser versus mechanical microkeratome.

ABSTRACT:

Purpose

To compare corneal endothelial cell density (ECD) and morphology between flap creation with a femtosecond laser and flap creation with a mechanical microkeratome 5 years after laser in situ keratomileusis (LASIK).

Setting

Mayo Clinic, Rochester, Minnesota, USA.

Design

Prospective randomized masked paired-eye study.

Methods

In this study of LASIK for myopia or myopic astigmatism, fellow eyes were randomized by ocular dominance to flap creation by a femtosecond laser or by a mechanical microkeratome. Central endothelial images were analyzed before and 3 years and 5 years after LASIK; endothelial cell variables were compared between treatments at each examination. Relationships between endothelial cell loss and contact lens wear, residual bed thickness, an

SUBMITTER: Klingler KN 

PROVIDER: S-EPMC3511658 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature