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Sister chromatids segregate at mitosis without mother-daughter bias in Saccharomyces cerevisiae.

ABSTRACT: There is evidence accumulating for nonrandom segregation of one or more chromosomes during mitosis in different cell types. We use cell synchrony and two methods to show that all chromatids of budding yeast segregate randomly and that there is no mother-daughter bias with respect to Watson and Crick-containing strands of DNA.

SUBMITTER: Keyes BE 

PROVIDER: S-EPMC3512160 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Sister chromatids segregate at mitosis without mother-daughter bias in Saccharomyces cerevisiae.

Keyes Brice E BE   Sykes Kenneth D KD   Remington Courtney E CE   Burke Daniel J DJ  

Genetics 20121010 4

There is evidence accumulating for nonrandom segregation of one or more chromosomes during mitosis in different cell types. We use cell synchrony and two methods to show that all chromatids of budding yeast segregate randomly and that there is no mother-daughter bias with respect to Watson and Crick-containing strands of DNA. ...[more]

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