Microscopic modeling of charge transport in sensing proteins.

ABSTRACT: : Sensing proteins (receptors) are nanostructures that exhibit very complex behaviors (ions pumping, conformational change, reaction catalysis, etc). They are constituted by a specific sequence of amino acids within a codified spatial organization. The functioning of these macromolecules is intrinsically connected with their spatial structure, which modifications are normally associated with their biological function. With the advance of nanotechnology, the investigation of the electrical properties of receptors has emerged as a demanding issue. Beside the fundamental interest, the possibility to exploit the electrical properties for the development of bioelectronic devices of new generations has attracted major interest. From the experimental side, we investigate three complementary kinds

SUBMITTER: Reggiani L 

PROVIDER: S-EPMC3512477 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature