139 Genetic Association Study of the IgE Immunodeficiency in Mexican Population

ABSTRACT:

Background

Primary immunodeficiencies (PID) are genetic diseases in which one or multiple components of the immune system, including cells (i.e. B cells, T cells, natural killer cells, phagocytes, complement components) or molecules (cytokines, chemokines, etc) are affected, leading to a low capacity to eliminate microorganisms and a high susceptibility to infection diseases. Most of the PID are multifactorial entities were the environmental and multiple genetic factor are involved. The single nucleotide polymorphisms (SNPs) analysis in case and control groups has been increasing the knowledge of the etiopathogenesis of several diseases and the opportunity to identify molecular markers useful in the clinical diagnosis.

Methods

We performed a case control study including 1

SUBMITTER: Malpica Cruz J 

PROVIDER: S-EPMC3512748 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature