Molecular typing of Coxiella burnetii from animal and environmental matrices during Q fever epidemics in the Netherlands.

ABSTRACT:

Background

The bacterium Coxiella burnetii has caused unprecedented outbreaks of Q fever in the Netherlands between 2007 and 2010. Since 2007, over 4000 human cases have been reported, with 2354 cases in 2009 alone. Dairy goat farms were identified as most probable sources for emerging clusters of human Q fever cases in their vicinity. However, identifying individual farms as primary source for specific clusters of human cases remains a challenge, partly due to limited knowledge of the different C. burnetii strains circulating in livestock, the environment and humans.

Results

We used a multiplex multi-locus variable number of tandem repeats analysis (MLVA) assay to investigate the genotypic diversity of C. burnetii in different types of samples that were collected nationwide

SUBMITTER: de Bruin A 

PROVIDER: S-EPMC3514391 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature