Immunogenetic Management Software: a new tool for visualization and analysis of complex immunogenetic datasets.

ABSTRACT: Here we describe the Immunogenetic Management Software (IMS) system, a novel web-based application that permits multiplexed analysis of complex immunogenetic traits that are necessary for the accurate planning and execution of experiments involving large animal models, including nonhuman primates. IMS is capable of housing complex pedigree relationships, microsatellite-based MHC typing data, as well as MHC pyrosequencing expression analysis of class I alleles. It includes a novel, automated MHC haplotype naming algorithm and has accomplished an innovative visualization protocol that allows users to view multiple familial and MHC haplotype relationships through a single, interactive graphical interface. Detailed DNA and RNA-based data can also be queried and analyzed in a highly accessible

SUBMITTER: Johnson ZP 

PROVIDER: S-EPMC3514553 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature