Distinct feedforward and intrinsic neurons in posterior inferotemporal cortex revealed by in vivo connection imaging.

ABSTRACT: We investigated circuits for object recognition in macaque anterior (TE) and posterior inferotemporal cortex (TEO), using a two-step method with in vivo anatomical imaging. In step 1, red fluorescent tracer was injected into TE to reveal and Pre-target patches of feedforward neurons in TEO. In step 2, these were visualized on the cortical surface in vivo, and injected with green fluorescent tracer. Histological processing revealed that patches >500 μm from the injection site in TEO consisted of intermingled green TEO intrinsically projecting neurons and red TEO-to-TE neurons, with only few double-labeled neurons. In contrast, patches near the injection site in TEO contained many double-labeled neurons. Two parallel, spatially intermingled circuits are suggested: (1) TEO neurons having very

SUBMITTER: Ichinohe N 

PROVIDER: S-EPMC3515805 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature