Genetically targetable and color-switching fluorescent probe.

ABSTRACT: Color bind: We have developed a probe TMR-para-MG that switches its fluorescence emission upon binding to a fluorogen-activating protein (FAP). In cells that express FAP, this dye labels target sites in one color and mitochondria in another color, thus it might be a suitable tool for monitoring changes in mitochondrial membrane potential.

SUBMITTER: Yushchenko DA 

PROVIDER: S-EPMC3517117 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature