Defining the predicted protein secretome of the fungal wheat leaf pathogen Mycosphaerella graminicola.

ABSTRACT: The Dothideomycete fungus Mycosphaerella graminicola is the causal agent of Septoria tritici blotch, a devastating disease of wheat leaves that causes dramatic decreases in yield. Infection involves an initial extended period of symptomless intercellular colonisation prior to the development of visible necrotic disease lesions. Previous functional genomics and gene expression profiling studies have implicated the production of secreted virulence effector proteins as key facilitators of the initial symptomless growth phase. In order to identify additional candidate virulence effectors, we re-analysed and catalogued the predicted protein secretome of M. graminicola isolate IPO323, which is currently regarded as the reference strain for this species. We combined several bioinformatic approach

SUBMITTER: Morais do Amaral A 

PROVIDER: S-EPMC3517617 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature