Dataset Information

Low Glycemic Index Carbohydrates versus All Types of Carbohydrates for Treating Diabetes in Pregnancy: A Randomized Clinical Trial to Evaluate the Effect of Glycemic Control.

ABSTRACT: Background. Due to the higher prevalence of obesity and diabetes mellitus (DM), more pregnant women complicated with diabetes are in need of clinical care. Purpose. Compare the effect of including only low glycemic index (GI) carbohydrates (CHO) against all types of CHO on maternal glycemic control and on the maternal and newborn's nutritional status of women with type 2 DM and gestational diabetes mellitus (GDM). Methods. Women (n = 107, ≤29 weeks of gestation) were randomly assigned to one of two nutrition intervention groups: moderate energy and CHO restriction (Group 1: all types of CHO, Group 2: low GI foods). Results. No baseline differences in clinical data were observed. Capillary glucose concentrations throughout pregnancy were similar between groups. Fewer women in Group 2 exceeded weight gain recommendations. Higher risk of prematurity was observed in women in Group 2. No differences in glycemic control were observed between women with type 2 DM and those with GDM. Conclusions. Inclusion of low GI CHO as part of a comprehensive nutrition intervention is equally effective in improving glycemic control as compared to all types of CHO. This strategy had a positive effect in preventing excessive maternal weight gain but increased the risk of prematurity.

SUBMITTER: Perichart-Perera O

PROVIDER: S-EPMC3517846 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Publications

Low Glycemic Index Carbohydrates versus All Types of Carbohydrates for Treating Diabetes in Pregnancy: A Randomized Clinical Trial to Evaluate the Effect of Glycemic Control.

Perichart-Perera Otilia O Balas-Nakash Margie M Rodríguez-Cano Ameyalli A Legorreta-Legorreta Jennifer J Parra-Covarrubias Adalberto A Vadillo-Ortega Felipe F

International journal of endocrinology 20121129

Background. Due to the higher prevalence of obesity and diabetes mellitus (DM), more pregnant women complicated with diabetes are in need of clinical care. Purpose. Compare the effect of including only low glycemic index (GI) carbohydrates (CHO) against all types of CHO on maternal glycemic control and on the maternal and newborn's nutritional status of women with type 2 DM and gestational diabetes mellitus (GDM). Methods. Women (n = 107, ≤29 weeks of gestation) were randomly assigned to one of ...[more]

PMID: 23251152

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Project description:Background: Fruits are a convenient and natural source of carbohydrates that can rapidly affect blood sugar levels and the glycemic index (GI). The GI plays a crucial role in the management of chronic diseases, including diabetes, obesity, hyperglycemia, and diet-related illnesses. Despite there being several health benefits linked with consuming fruits, it remains unclear which specific components of fruits are the key determinants that significantly influence the GI. Methods: This study retrospectively examined the relationship between different types of carbohydrates and the GI of various fruits to determine their correlation. The fruits' sugar and fiber contents were identified from available public databases, the U.S. Department of Agriculture (USDA), FooDB, PubMed, and published sources. Results: Previously, the GI was determined by the available carbohydrates, which include different types of sugar. In this study, individual hexose sugars, along with the total carbohydrates and dietary fiber, were examined. The results indicated a strong correlation between fructose and the GI, whereas glucose and total glucose did not exhibit such a correlation. The total carbohydrate-to-fiber ratio displayed a stronger correlation (R = 0.57 and p > 0.0001) with the GI compared to glucose alone (R = 0.37; p = 0.01) or the total glucose (R = 0.45; p = 0.0009) with the consideration of fiber, while the scattering of data points around the regression line suggested that factors beyond the total carbohydrate and fiber also contribute to determining the GI. Conclusions: This study demonstrated that individual hexose sugars, especially fructose, significantly influence the GI. These findings suggest that the carbohydrate-to-fiber ratio may offer a more accurate and reliable metric for determining the GI than traditional methods. Further research is warranted to investigate the specific contribution of dietary fiber components, fruit texture, micronutrients, vitamins, genetic predispositions, gut microbiota, and the body's physiological status to gain a deeper understanding of GI regulation.

Dataset Information

Low Glycemic Index Carbohydrates versus All Types of Carbohydrates for Treating Diabetes in Pregnancy: A Randomized Clinical Trial to Evaluate the Effect of Glycemic Control.

Publications

Low Glycemic Index Carbohydrates versus All Types of Carbohydrates for Treating Diabetes in Pregnancy: A Randomized Clinical Trial to Evaluate the Effect of Glycemic Control.

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