Surface chemistry-mediated penetration and gold nanorod thermotherapy in multicellular tumor spheroids.

ABSTRACT: We investigated the penetration and thermotherapy efficiency of different surface coated gold nanorods (Au NRs) in multicellular tumor spheroids. The current data show that negatively charged Au NRs, other than positively charged Au NRs, can penetrate deep into the tumor spheroids and achieve a significant thermal therapeutic benefit.

SUBMITTER: Jin S 

PROVIDER: S-EPMC3518646 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature