Resection of ictal high-frequency oscillations leads to favorable surgical outcome in pediatric epilepsy.

ABSTRACT:

Purpose

Intracranial electroencephalography (EEG) is performed as part of an epilepsy surgery evaluation when noninvasive tests are incongruent or the putative seizure-onset zone is near eloquent cortex. Determining the seizure-onset zone using intracranial EEG has been conventionally based on identification of specific ictal patterns with visual inspection. High-frequency oscillations (HFOs, >80 Hz) have been recognized recently as highly correlated with the epileptogenic zone. However, HFOs can be difficult to detect because of their low amplitude. Therefore, the prevalence of ictal HFOs and their role in localization of epileptogenic zone on intracranial EEG are unknown.

Methods

We identified 48 patients who underwent surgical treatment after the surgical evaluation with

SUBMITTER: Fujiwara H 

PROVIDER: S-EPMC3520059 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature